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November 1982

Thick-Filament Degeneration Associated With Periarteritis Nodosa

Author Affiliations

From the Department of Internal Medicine, Hadassah University-Hospital-Mt Scopus (Drs Halperin, Kobrin, Ilsar, and Lugassy), and the Department of Pathology, Hebrew University Hadassah Medical School (Dr Yarom), Jerusalem.

Arch Neurol. 1982;39(11):730-732. doi:10.1001/archneur.1982.00510230056018

• Absence of thick filaments from A bands in 30% of myofibers, which gave apparently normal histochemical reactions for myosin adenosine triphosphatase, was seen in a case of periarteritis nodosa. The pathogenesis of the condition remains uncertain, but immunologic, toxic, or viral causation may be involved. This pathological change seems to be reversible with a good prognosis.

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