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December 1982

Modulation of Purkinje Cell Firing Rates by Surface Stimulation in the Cat

Author Affiliations

From the Department of Neurosurgery, Medical College of Wisconsin, Milwaukee (Drs Bilof, Boehmer, and Larson); the Biomedical Engineering Program, Marquette University College of Engineering and Medical College of Wisconsin, Milwaukee (Dr Sances); and the Department of Surgery, Shriners Hospital for Crippled Children, Chicago (Dr Millar). Dr Bilof is now with Travenol Laboratories, Round Lake, Ill; Dr Boehmer is now with Ohio Medical Products, Madison, Wis.

Arch Neurol. 1982;39(12):765-768. doi:10.1001/archneur.1982.00510240027007

• Purkinje cell microelectrode recordings have been obtained in the presence of high-stimulus artifact during cerebellar surface stimulation. The results obtained suggest that an important relationship exists between stimulus frequency and spontaneous Purkinje cell firing rate. Purkinje cells respond to surface stimulation by initial excitation, followed by inhibition.

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