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February 1983


Author Affiliations

Department of Neurology University of Rochester School of Medicine and Dentistry 601 Elmwood Ave Rochester, NY 14642

Arch Neurol. 1983;40(2):128. doi:10.1001/archneur.1983.04050020090027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Neuroimmunology, as defined by Jeremy Brockes in the preface to this book, is the application of immunologic methods to major problems in neurobiology. Although this definition is a restricted one, Brockes appropriately emphasizes several areas of neurobiology that can be effectively approached by new and rapidly evolving immunologic methods, thereby indicating the scope and purpose of the book.

What follows is a collection of brief but admirably comprehensive reviews of such subjects as the application of monoclonal antibodies to studies of neuromuscular junction, muscle membranes, CNS synapses, neuronal and glial antigenic heterogeneity, and retina. In addition, functional lymphoid cell subsets and immunopathologic disorders of the CNS are included. The information is presented readably and effectively, despite contributions from multiple authors.

Many examples are provided of the use of monoclonal antibodies to study nervous system development and define neuronal and glial heterogeneity, and as a tool for isolation, purification, and, ultimately

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