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Article
May 1983

An Erythrocyte Membrane Antigen Associated With X-Linked Muscular Dystrophy

Author Affiliations

From the Division of Medical Genetics, Department of Pediatrics and Child Health, Howard University College of Medicine, Washington, DC.

Arch Neurol. 1983;40(5):300-305. doi:10.1001/archneur.1983.04050050068010
Abstract

• Goat antiserum was prepared against erythrocyte membranes obtained from a man who had X-linked muscular dystrophy. When cross-adsorbed with control membranes and tested on double immunodiffusion plates or by binding to intact erythrocytes suspended in thinlayer agar plates, this antiserum discriminated between membranes from phenotypically normal controls and dystrophic men, and between controls and obligate female dystrophy carriers. It also identified two populations among a small sample of women at risk for being dystrophy carriers.

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