• Twenty-four patients with well-documented Friedreich's ataxia underwent quantitative oculomotor testing. A consistent pattern of eye movement abnormalities was observed. This pattern included fixation instability, inaccurate saccades with normal peak velocity, impaired smooth pursuit and optokinetic slow phases, decreased vestibulo-ocular reflex gain, and impaired visual-vestibular interaction. This pattern corresponds to the known pathologic changes of Friedreich's ataxia and can be useful in the differential diagnosis of cerebellar atrophy.
Furman JM, Perlman S, Baloh RW. Eye Movements in Friedreich's Ataxia. Arch Neurol. 1983;40(6):343–346. doi:10.1001/archneur.1983.04050060043006
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