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June 1983

Eye Movements in Friedreich's Ataxia

Author Affiliations

From the Reed Neurological Research Center, Department of Neurology, UCLA School of Medicine.

Arch Neurol. 1983;40(6):343-346. doi:10.1001/archneur.1983.04050060043006

• Twenty-four patients with well-documented Friedreich's ataxia underwent quantitative oculomotor testing. A consistent pattern of eye movement abnormalities was observed. This pattern included fixation instability, inaccurate saccades with normal peak velocity, impaired smooth pursuit and optokinetic slow phases, decreased vestibulo-ocular reflex gain, and impaired visual-vestibular interaction. This pattern corresponds to the known pathologic changes of Friedreich's ataxia and can be useful in the differential diagnosis of cerebellar atrophy.

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