[Skip to Content]
[Skip to Content Landing]
July 1983

Myelopathy After Herpes Zoster

Author Affiliations

From the Department of Medicine, Mercy Hospital of Pittsburgh.

Arch Neurol. 1983;40(7):445-446. doi:10.1001/archneur.1983.04050070075020

• A 73-year-old woman with a remote history of carcinoma of the ovary had herpes zoster involving several lumbosacral dermatomes. There subsequently developed a progressive myelopathy with normal myelographie findings and CSF pleocytosis. Vidarabine (15 mg/kg/day) was given for ten days. No further progression occurred. The syndrome of progressive myelopathy following herpes zoster is rare; direct viral invasion of the cord with subsequent necrosis appears to be the pathogenic mechanism. Antiviral therapy may have halted progression, but it did not lead to recovery of function.