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July 1983

Subacute Toxic Delirium Following Nitrous Oxide Abuse

Author Affiliations

From the Department of Neurology, State University of New York at Stony Brook.

Arch Neurol. 1983;40(7):446-447. doi:10.1001/archneur.1983.04050070076021

• Nitrous oxide (N20) abuse has been associated with myeloneuropathy, but significant mental status changes rarely have been described. We treated a patient in whom a subacute delirium developed after heavy N20 abuse; symptoms slowly cleared over three weeks after removal of the neurotoxln.

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