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September 1983

Nonsurgical Treatment of Cerebral Nocardiosis

Author Affiliations

From the Departments of Medicine (Drs Norden and Ruben) and Neurosurgery (Selker), Montefiore Hospital, Pittsburgh, and University of Pittsburgh School of Medicine.

Arch Neurol. 1983;40(9):594-595. doi:10.1001/archneur.1983.04050080094024

• In previously healthy, 49-year-old man, CNS infection due to Nocardia asteroides was manifested initially as sterile meningitis and then as a single large brain abscess and was treated successfully with medical therapy alone. Resolution of the brain abscess was documented with serial computed tomographic scans. The strain of N asteroides was sensitive to both sulfisoxazole and ampicillin. Although surgical intervention must always be considered in the treatment of brain abscess caused by N asteroides, medical therapy is preferable if the patient responds initially.