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Article
November 1983

Achondroplasia Associated With Obstructive Sleep Apnea

Author Affiliations

Department of Neurology
Department of Internal Medicine
Division of Otolaryngology University of Utah Medical Center Salt Lake City, UT 8$132

Arch Neurol. 1983;40(12):769. doi:10.1001/archneur.1983.04050110087019
Abstract

To the Editor.  —Among the many neurologic complications of achondroplasia,1 serious respiratory impairment has been treated primarily by posterior fossa craniectomy and decompression.2 However, specific pathophysiologic classification of the respiratory symptom may lead to an alternative solution.

Report of a Case.  —A 45-year-old achondroplastic man suffered from severe daytime sleepiness, which had gradually increased during three years. Treatment for narcolepsy provided temporary symptomatic relief. Only active labor and eating could keep him from falling asleep during the day. His nocturnal sleep was restless and interrupted by respiratory pauses. His snoring had become extremely annoying to his family. Besides the patient's stature and radiologic appearances typical of achondroplasia,1 physical and neurologic examination results were entirely normal.A sleep apnea study3 during a daytime nap lasting 52 minutes showed 92 apneic periods (respiratory pauses lasting 10 s or longer; 107 apneas per hour). Fifty-two of these apneic periods

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