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Original Contributions
December 1983

Pergolide in Parkinson's Disease

Author Affiliations

From the Department of Neurological Sciences, Rush-Presbyterian St Luke's Medical Center, Chicago.

Arch Neurol. 1983;40(13):785-787. doi:10.1001/archneur.1983.04050120035003

•Twenty-two patients received pergolide mesylate for Parkinson's disease for one year. Improvement was maximal at six months, but average functional scores were still better at 12 months than at pretreatment evaluation. On-off fluctuations were reduced in severity, and two of 18 patients experienced full resolution. Pergolide is an effective and safe ongoing medication for Parkinson's disease.

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