Letters to the editor should be submitted as an original and two duplicates. They should be typewritten double-spaced on plain bond paper; they will be subject to editing. A copyright transmittal letter signed by all authors must accompany this (see "Instructions for Authors").
To the Editor.
—Cataplexy, which usually occurs as part of a narcoleptic syndrome, is characterized by a sudden loss of muscle tone in an alert patient, frequently triggered by emotional upset or physical exercise. It is thought to be closely related to atony in paradoxical sleep.1 Various pharmacologic treatments for narcolepsy and cataplexy have been reported in recent years.2There is general agreement that excessive daytime sleepiness and irresistible sleep attacks are best relieved by amphetamine derivatives such as methylphenidate hydrochloride or pemoline.3 In contrast, cataplexy and sleep paralysis are better controlled by tricyclic antidepressant agents, especially clomipramine hydrochloride4 and protryptiline hydrochloride.5
Paulus W, Hömberg V, Noth J. Cataplexy Relieved by Tiapride. Arch Neurol. 1983;40(13):828. doi:10.1001/archneur.1983.04050120078016
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: