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Letters to the Editor
December 1983

Sweet's Syndrome With Neurologic Signs and Psychiatric Symptoms

Author Affiliations

Departments of Psychiatry and Neurology Asahikawa Medical College Asahikawa, Hokkaido, 078-11 Japan

Arch Neurol. 1983;40(13):829. doi:10.1001/archneur.1983.04050120079018

To the Editor.  —Since Sweet1 reported eight cases of acute febrile neutrophilic dermatosis, more than 100 cases of Sweet's syndrome have been reported by investigators.2 The syndrome is considered to have the following features: fever, raised painful plaques, polymorphonuclear leukocytosis, and dense neutrophil infiltration in the dermis. I examined a man with neurologic signs and psychiatric symptoms, none of which have been described previously, to my knowledge.

Report of a Case.  —A 46-year-old man had an episode of fever and raised painful plaques within several weeks that recurred for ten years, once or twice per year. These episodes were often preceded by tonsillitis. Steroids had a beneficial effect on these signs and symptoms.The patient was admitted to the hospital on Oct 16, 1980, because of several days of fever with plaque formation, followed by convulsions. On admission, his responsiveness was slightly reduced, and an EEG showed anterior

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