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Research in multiple sclerosis (MS) has accelerated during the past 15 years. Major advances have been made in the areas of epidemiology, diagnostic testing, genetics, immunology, and experimental demyelination. Information in these areas has accumulated so rapidly that the most recent comprehensive textbook on MS, by McAlpine et al (Multiple Sclerosis: A Reappraisal, ed 2, New York, Churchill Livingstone, 1972), contains inadequate information in virtually all of these areas. For this reason, Multiple Sclerosis represents a needed thorough update.
Noted experts in their respective fields have contributed chapters ranging from the molecular biology of myelin to the comprehensive care of the patient with MS. Although the material is comprehensive, I found the chapters readable. Of particular note were the chapters on epidemiology by Kurtzke, genetics by Stewart and Kirk, CSF by Walsh and Tourtellotte, immunology by Leibowitz, and comprehensive treatment of patients with MS by Tourtellotte et al.
Rudick RA. Multiple Sclerosis. Arch Neurol. 1983;40(13):832c. doi:10.1001/archneur.1983.04050120082025
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