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April 1984

Muscular Hypertrophy After Chronic Radiculopathy

Author Affiliations

From the Clinica Neurologica (Drs Montagna, Martinelli, Cirignotta, and Lugaresi) and Istituto di Microscopia Elettronica Clinica e Consultorio per lo studio e la diagnosi delle miopatie (Dr Govoni), Università di Bologna, Bologna, Italy, and the Divisione di Neurologia, Ospedale di Forli (Dr Rasi), Forli, Italy.

Arch Neurol. 1984;41(4):397-398. doi:10.1001/archneur.1984.04050160059017

• In four patients, calf muscular hypertrophy developed after the onset of sciatica. Hypertrophic muscles were weak and showed electromyographic signs of denervation. In all cases, calf muscle biopsy showed striking hypertrophy of type 1 and, especially, type 2 muscle fibers. This hypertrophy was associated with other signs indicating a neurogenic lesion. Muscle hypertrophy is a rare finding in neurogenic lesions. Stretch and exercise of muscle are probably the causative factors.

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