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May 1984

Neuroendocrinologic Findings in Patients With Untreated Huntington's Chorea

Author Affiliations

From the Department of Neurology, C. Besta Neurologic Institute, Milan, Italy (Drs Caraceni, Parati, Giovannini, Grassi, Scigliano, and Carella), and the Institute of Pharmacology, University of Milan, Milan, Italy (Drs Martinez-Campos, Novelli, and Müller). Dr Martinez-Campos is now at the Unidad de Medicina Bio Psico Social Hospital General de Mexico, Mexico City.

Arch Neurol. 1984;41(5):516-520. doi:10.1001/archneur.1984.04050170062019

• Huntington's chorea (HC) was studied in 14 untreated patients, in six patients receiving long-term neuroleptic treatment, and in four patients after drug withdrawal. Our results showed that patients with HC may be divided into three groups, otherwise clinically indistinguishable, on the basis of growth hormone responsiveness to dopaminergic stimuli. The existence of subpopulations of patients with HC must be considered in further studies on these subjects.

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