We studied a man affected with facioscapulohumeral muscular dystrophy (FMD) and multiple sclerosis (MS). This association has not been previously reported, to our knowledge. As a chance occurrence, it would be encountered less than once in 109 in the world population.
REPORT OF A CASE
At age 16 years, the patient noticed weakness of the proximal parts of the upper extremities and atrophy of both pectoralis muscles. At age 23 years he had an episode of temporary (six weeks) loss of vision in the left eye. On examination at 26 years of age there was moderate atrophy and weakness of the pectoralis, biceps, and triceps muscles, with winging of the scapulas. At this time, his physician (J.M.H.) commented that the patient appeared to have both dystrophy and MS. This was met with disbelief by one of us (R.D.C.). Results of the neurologic examination were otherwise normal. A lumbar puncture
Mishra SK, Currier RD, Smith EE, Malhotra C, Bebin J, Hudson JM. Facioscapulohumeral Dystrophy Associated With Multiple Sclerosis. Arch Neurol. 1984;41(5):570–571. doi:10.1001/archneur.1984.04050170120032
Neurology in JAMA: Read the Latest
Customize your JAMA Network experience by selecting one or more topics from the list below.