[Skip to Navigation]
July 1984

Paroxysmal Dystonia as the Initial Manifestation of Multiple Sclerosis

Author Affiliations

From the Departments of Neurology, University of Miami School of Medicine (Drs Berger and Sheremata) and Hadassah Hospital, Hebrew University School of Medicine, Jerusalem (Dr Melamed).

Arch Neurol. 1984;41(7):747-750. doi:10.1001/archneur.1984.04050180069020

• Paroxysmal dystonia was the initial manifestation of multiple sclerosis (MS) in eight patients. The disorder was generally characterized by dystonic posturing of unilateral extremities, averaging less than one minute in duration. Facial grimacing and dysarthria occurred in two of the eight patients. This paroxysmal phenomenon was frequently the cause of diagnostic confusion. The time elapsing before other neurological symptoms of MS developed was as long as ten years.

Add or change institution