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July 1984

Progressive Multifocal Leukoencephalopathy in a Patient With Acquired Immune Deficiency Syndrome

Author Affiliations

From the Departments of Neurology (Dr Bernick) and Pathology (Dr Gregorios), Jackson Memorial Hospital, Miami.

Arch Neurol. 1984;41(7):780-782. doi:10.1001/archneur.1984.04050180102028

• Progressive multifocal leukoencephalopathy (PML) occurred in a heterosexual Haitian man with acquired immune deficiency syndrome (AIDS). The patient initially had focal neurologic signs and nonenhancing lesions on a computed tomographic scan. Although PML is rare, it should be included in the differential diagnosis of opportunistic infections associated with AIDS. Brain biopsy is suggested in patients suspected of having PML who might benefit from antiviral therapy.

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