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Article
July 1984

Intravenous Calcium Treatment of Refractory Hypotension in Reye's Syndrome

Author Affiliations

From the Divisions of Anesthesia (Dr Jones) and Pediatric Neurology (Dr Thompson), Primary Children's Medical Center, Salt Lake City; Department of Allied Health Sciences, Weber State University, Ogden, Utah (Dr Jones); and Department of Pediatrics, University of Utah, Salt Lake City (Dr Thompson).

Arch Neurol. 1984;41(7):786-787. doi:10.1001/archneur.1984.04050180112030
Abstract

• Hypotension refractory to volume infusion and sympathomimetic drugs developed in a child with Reye's syndrome who had received prochlorperazine prior to admission. Calcium chloride given intravenously restored autonomictone, resulting in restoration of a normal BP and cerebral perfusion pressure. Calcium may reverse the hypotensive effects of prochlorperazine maleate and may help reverse hypotension in patients with Reye's syndrome who have been pretreated with phenothiazine antiemetics.

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