—We thank Drs Zetusky and Jankovic for their thoughtful comments, with which we are largely in agreement. Early in their letter they stated that "the population sample was small"; we certainly agree with that observation.We welcome this opportunity to provide additional detail not included in the original report, as well as some corrections to minor misreadings by Drs Zetusky and Jankovic. Bradykinesia was given the most weight in our clinical assessment because it is often the single feature of Parkinson's disease that results in the greatest functional impairment.We disagree with Drs Zetusky and Jankovic that the results of our study indicate that the PDL group had more severe bradykinesia, while the PDR group had more marked tremor. As shown in Table 1 of our article, there were no statistically significant differences in those features between the PDL and PDR groups. Nonetheless, the association of bradykinesia and intellectual impairment
Direnfeld LK, Volicer L, Langlais PJ, Marquis J, Albert ML. Laterality and Symptom Association in Parkinson's Disease-Reply. Arch Neurol. 1985;42(12):1132–1133. doi:10.1001/archneur.1985.04060110010002
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