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Article
February 1986

Neurologic Correlates of Osteogenesis Imperfecta

Author Affiliations

From the Departments of Pediatrics (Drs Tsipouras, Barabas, and Matthews) and Biochemistry (Dr Tsipouras), UMDNJ-Rutgers Medical School, Piscataway, NJ. Dr Matthews is now at Monmouth Medical Center, Long Branch, NJ.

Arch Neurol. 1986;43(2):150-152. doi:10.1001/archneur.1986.00520020044016
Abstract

• The neurologic status of ten patients with osteogenesis imperfecta (OI) was evaluated. Four patients with mild OI (type I) had normal neurologic findings and normal computed tomographic scans. Three of these four patients had macrocephaly. All six patients with severe OI (type III) had cortical atrophy on computed tomographic scan and three were also macrocephalic.

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