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February 1986

Unusual Acute Neurologic Presentations With Epstein-Barr Virus Infection

Author Affiliations

From the Departments of Pediatrics (Drs Leavell, Ray, and Ferry), Pathology (Dr Ray and Ms Minnich), and Neurology (Dr Ferry), University of Arizona College of Medicine, Tucson.

Arch Neurol. 1986;43(2):186-188. doi:10.1001/archneur.1986.00520020072025

• We describe two patients with serologic evidence of active Epstein-Barr virus infection who presented with unusual neurologic manifestations and minimal systemic findings of infectious mononucleosis. One girl developed an acute hemiplegic migraine syndrome followed by acute psychosis, and the other patient had severe, generalized chorea. The wide spectrum of presenting central nervous system findings associated with Epstein-Barr virus infections underscores the need to suspect this agent in a variety of acute neurologic syndromes.