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May 1986

Chronic Human Colchicine Neuropathy and Myopathy

Arch Neurol. 1986;43(5):521-523. doi:10.1001/archneur.1986.00520050091033

• A 43-year-old woman who indiscriminately took colchicine for five years developed a progressive multisystem syndrome that included severe axonal neuropathy and a pathologically striking myopathy. The neuropathy and myopathy were similar to experimental animal colchicine-induced neuromuscular toxicity.