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November 1986

Spinal Myoclonus Associated With HTLV III/LAV Infection

Arch Neurol. 1986;43(11):1203-1204. doi:10.1001/archneur.1986.00520110089026

• We describe spinal myoclonus in a 35-year-old homosexual man with concurrent human T-cell lymphotropic virus type III / lymphadenopathy - associated virus (HTLV III/LAV) infection of the central nervous system as indicated by intrablood-brain barrier synthesis of HTLV III/ LAV-specific IgG. The spinal myoclonus was characterized by asymmetric, rhythmic contractions of the abdomen with a frequency ranging between 40 and 70 per minute. The myoclonus was self-limited, resolving over the course of two months. Human T-cell lymphotropic virus type III/lymphadenopathy - associated virus should be considered among the viral causes of spinal myoclonus.