• Diagnosis of embolic stroke is based on identification of a source of embolus (SOE) and on neurologic symptoms acknowledged as "clinical criteria." To test the validity of these criteria, we analyzed the symptoms at onset in 193 patients hospitalized after acute cerebral infarction. Patients were grouped according to identification of a cardiac SOE (106 patients), an arterial SOE (38 patients), or no SOE (49 patients). Cross-tabulations demonstrated that only rapidity and loss of consciousness at onset were associated with the presence of a cardiac SOE to a significant degree. Although these symptoms were highly specific for cardiac SOE, they were not sensitive. A distinct clinical neurologic profile from the symptoms and mode of onset was not identified.
Ramirez-Lassepas M, Cipolle RJ, Bjork RJ, et al. Can Embolic Stroke Be Diagnosed on the Basis of Neurologic Clinical Criteria? Arch Neurol. 1987;44(1):87–89. doi:10.1001/archneur.1987.00520130067019
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.