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June 1987

Clinical Electrophysiologic Studies of HTLV-I-Associated Myelopathy

Author Affiliations

From the Third Department of Internal Medicine, Kagoshima (Japan) University Faculty of Medicine.

Arch Neurol. 1987;44(6):609-612. doi:10.1001/archneur.1987.00520180033012

• Six patients with human T-cell lymphotropic virus type I (HTLV-I)—associated myelopathy (HAM) were studied by electrophysiologic methods. Upper-limb short-latency somatosensory evoked potentials showed slight delay of the N9-N20 interpeak latency in one of 12 limbs, while the lower-limb short-latency somatosensory evoked potentials showed prolonged N20-P40 interpeak latency in eight of 12 limbs. Frequent polyphasic potentials and occasional giant spikes were observed in the distal extremities. F-wave conduction velocity was delayed in some patients. Results of the other nerve conduction studies were unremarkable. Our data provide a valuable extension of the clinical examination of HAM and offer encouragement for a more extensive electrophysiologic study of this entity, especially in the spinal cord.

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