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June 1987

Behavioral Manifestations of Central Pontine Myelinolysis

Author Affiliations

From the Division of Neuroscience and Behavioral Neurology, Charles A. Dana Research Institute, Beth Israel Hospital, Boston.

Arch Neurol. 1987;44(6):671-673. doi:10.1001/archneur.1987.00520180085025

• A young woman with a clinical history and magnetic resonance imaging scan consistent with central pontine myelinolysis came to medical attention because of prominent behavioral symptoms. Marked clinical recovery occurred despite persistent radiologic abnormalities. Rapid correction of hyponatremia was probably related to the development of the central pontine myelinolysis. A normal computed tomographic scan and the absence of brain-stem signs delayed accurate diagnosis.

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