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October 1987

Pure Motor Hemiplegia due to Meningovascular Neurosyphilis

Author Affiliations

From the Departments of Neurology (Drs Johns and Parker) and Medicine (Infectious Disease Unit) (Dr Tierney), Massachusetts General Hospital, Boston. Dr Johns is now with the Department of Neurology, Johns Hopkins University School of Medicine, Baltimore.

Arch Neurol. 1987;44(10):1062-1065. doi:10.1001/archneur.1987.00520220060018

• Two young male homosexuals developed prodromal syndrome followed by penicillin-responsive meningitis and the acute onset of pure motor hemiplegia. The clinical and laboratory features are consistent with meningovascular neurosyphilis. Basis pontis infarctions were subsequently demonstrated on magnetic resonance imaging scans. To our knowledge, this is the first description of syphilitic arteritis as a pathophysiologic basis for pure motor hemiplegia.

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