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Article
November 1987

Progressive Dystonia With Bilateral Putaminal Hypodensities

Author Affiliations

From the Montreal Neurological Institute and the Department of Neurology and Neurosurgery, McGill University, Montreal (Drs Berkovic, Karpati, and Carpenter), and the Division of Neurology, Toronto Western Hospital (Dr Lang).

Arch Neurol. 1987;44(11):1184-1187. doi:10.1001/archneur.1987.00520230064016
Abstract

• Three unrelated patients, aged 4, 18, and 47 years, had generalized dystonia associated with bilateral striatal hypodensities on computed tomography. Mitochondrial encephalopathy was considered to be the most likely diagnosis, but this could not be proved. These patients confirm previous reports linking acquired generalized dystonia with bilateral putaminal lesions and they highlight the problem in differential diagnosis of this clinicoradiologic syndrome.

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