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December 1987

Guillain-Barré Syndrome Following Campylobacter jejuni Enteritis

Author Affiliations

University of Vermont College of Medicine Burlington, VT 05405
University of Rochester School of Medicine and Dentistry Rochester, NY 14642

Arch Neurol. 1987;44(12):1219. doi:10.1001/archneur.1987.00520240005002

To the Editor.  —We have treated a patient in whom the Guillain-Barré syndrome (GBS) developed 13 days after the onset of febrile diarrhea caused by Campylobacter jejuni. In only seven previously reported cases of GBS has C jejuni been isolated from stool,1-6 and no such cases (identified either serologically or by culture) have previously been described from countries other than England. Nevertheless, recent reports from England have indicted C jejuni, on serologic evidence, as the "most common single identifiable pathogen precipitating the disease," outranking both cytomegalovirus and Epstein-Barr virus combined.7

Report of a Case.  —A 69-year-old man was admitted to a hospital near Watertown, NY, for prostatic surgery and lithotripsy, but those elective procedures were deferred when diarrhea developed, with temperature as high as 39.4°C (103°F). Campylobacter jejuni was cultured from his stool. Erythromycin therapy was instituted, and he was discharged; his diarrhea ceased in about ten days.