• The diagnosis of a "serous apoplexy," customary in the first half of the 19th century, was based on the lack of knowledge regarding the normal presence of the cerebrospinal fluid. Balzac's descriptions of three cases of serous apoplexy draw our attention to the fact that the discovery of the cerebrospinal fluid by François Magendie was not assimilated into clinical medicine until the second half of the 19th century.
van den Doel EMH. Balzac's Serous Apoplexies: The Hesitant Acceptance of the Discovery of the Cerebrospinal Fluid by Magendie. Arch Neurol. 1987;44(12):1303–1305. doi:10.1001/archneur.1987.00520240073017
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.