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May 1988

Subacute Structural Myopathy Associated With Human Immunodeficiency Virus Infection

Author Affiliations

From the Departments of Pathology (Drs Gonzales, Greco, and DeArmond) and Neurology (Drs Olney, So, McQuinn, and Miller), University of California at San Francisco; the Departments of Pathology (Dr Greco) and Neurology (Dr Miller), Children's Hospital of San Francisco; and the Department of Anatomical Pathology, Royal Melbourne Hospital (Dr Gonzales).

Arch Neurol. 1988;45(5):585-587. doi:10.1001/archneur.1988.00520290125026

• An unusual myopathy characterized by selective loss of thick filaments and widespread formation of rod bodies is described in two men, both seropositive for human immunodeficiency virus. We were unable to find any previous reports documenting this combination of morphological abnormalities, which we believe may be related to human immunodeficiency virus infection. Both patients responded to treatment: one, to steroid therapy; the other, to plasmapheresis.

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