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June 1988

Blood Flow Imaging of a Posterior Circulation Stroke: Use of Technetium Tc 99m Hexamethylpropyleneamine Oxime and Single Photon Emission Computed Tomography

Author Affiliations

From the Departments of Neurology (Dr Foster and Ms Bluelein) and Internal Medicine (Drs Mountz and Kuhl and Mr Ackerman and Mr Petry), University of Michigan Medical Center, Ann Arbor.

Arch Neurol. 1988;45(6):687-690. doi:10.1001/archneur.1988.00520300107029

• Regional cerebellar perfusion was imaged using technetium Tc 99m hexamethylpropylene amine oxime and single photon emission computed tomography (HM-PAO-SPECT) in a patient with chronic left lateral medullary syndrome with contralateral weakness due to traumatically induced thrombosis of the left vertebral artery. Despite continued neurologic deficits, x-ray transmission computed tomography was normal. However, HM-PAOSPECT demonstrated that blood flow to the left cerebellar hemisphere was significantly impaired. This abnormality was still apparent after correction for atrophy as estimated by magnetic resonance imaging. Technetium Tc 99m hexamethylpropyleneamine oxime and single photon emission computed tomography effectively imaged regional blood flow in the vertebrobasilar circulation and appears to more clearly reflect the nature and extent of the neurologic deficit than either x-ray transmission computed tomography or magnetic resonance scanning.

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