• Direct electron microscopic immunohistochemistry of the sural nerve of a patient with neuropathy and an IgMk paraprotein demonstrated that immunoglobulin was deposited throughout the compact myelin. These findings support the notion that immunoglobulin deposition plays a role in the pathogenesis of the neuropathy in vivo.
Mata M, Kahn SN, Fink DJ. A Direct Electron Microscopic Immunocytochemical Study of IgM Paraproteinemic Neuropathy. Arch Neurol. 1988;45(6):693–697. doi:10.1001/archneur.1988.00520300113031
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