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July 1988

Periodic Sharp Waves in Baclofen-Induced Encephalopathy

Arch Neurol. 1988;45(7):814-815. doi:10.1001/archneur.1988.00520310132033

• Acute encephalopathy and an abnormal electroencephalogram with a periodic sharp wave pattern developed in a 58-year-old woman shortly after she received a few doses of baclofen. The clinical and electroencephalographic abnormalities improved promptly after the medication was discontinued.