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December 1988

Normal Brain-Stem Auditory Evoked Potentials With Abnormal Latency-Intensity Studies in Patients With Acoustic Neuromas

Author Affiliations

From the Departments of Neurology (Drs Legatt, Pedley, and Emerson), Neurosurgery (Dr Stein), and Otolaryngology (Dr Abramson), The College of Physicians and Surgeons of Columbia University, New York. Dr Legatt is now with the Department of Neurology, Albert Einstein College of Medicine, Bronx, NY.

Arch Neurol. 1988;45(12):1326-1330. doi:10.1001/archneur.1988.00520360044010

• Brain-stem auditory evoked potentials (BAEPs) are highly sensitive for detecting acoustic neuromas but false-negative results occur. We studied BAEPs preoperatively in 39 cases of acoustic neuroma. Absolute and interpeak latencies ipsilateral to the tumor, and interaural latency differences, were normal in four patients with small tumors. In three of these, however, results of latency-intensity studies were abnormal. In one patient, the latency-intensity result became normal postoperatively. If acoustic neuroma is suspected, and BAEPs are normal by usual criteria, latency-intensity functions should be examined to maximize chances of detecting a small tumor.

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