[Skip to Navigation]
Article
May 1989

Agenesis of the Corpus Callosum in Apert Syndrome?

Author Affiliations

Guillermo DE León Department of Neurology
Department of Pediatrics
Department of Anatomic Pathology
Department of Surgery Temple University School of Medicine Philadelphia, PA 19140

Arch Neurol. 1989;46(5):479. doi:10.1001/archneur.1989.00520410013005
Abstract

To the Editor.  —We wish to reply to the letter to the editor by Jeret et al1 that appeared in the January issue of the Archives.It was clearly stated in our article2 that agenesis of the corpus callosum is not a consistent feature of Apert syndrome, and that the callosal malformation is obviously not required to define the disease. We suggested that limbic malformation, with or without agenesis of the corpus callosum, is "probably more common in Apert syndrome than previously thought." The early development and the wide-spread nature of the basic pathologic process were also emphasized in our report. Therefore, it seems that the comments by Jeret et al are superfluous, and that the main purpose of their letter is simply to call attention to the future publication of their two articles on callosal agenesis. We look forward to reading them.

Add or change institution
×