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May 1989

Medial Thalamus and Memory

Author Affiliations

Neurology Service Hyogo Brain and Heart Center at Himeji 520 Saisho-ko Himeji 670, Japan

Arch Neurol. 1989;46(5):482-483. doi:10.1001/archneur.1989.00520410016012

To the Editor.  —We read with great interest the article by Kritchevsky et al1 describing two patients who did not develop any memory defect after infarction in the dorsomedial (DM) nucleus of the thalamus. To localize the lesion, and to estimate the volume of the nucleus involved, they used magnetic resonance imaging (MRI) with a stereotaxic method, a modification of that described by Archer et al2 and Graff-Radford et al.3 One patient had a right-sided lesion involving about 15% of the DM nucleus, and the other had bilateral lesions that affected about 15% of the left side of the DM nucleus and less than 5% of the right side of the DM nucleus.In the stereotaxic method they used, errors on the order of millimeters can inevitably arise. First, although they used the center of the lesion as a reference point, it is difficult to determine the

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