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May 1989

Electroencephalographic Abnormalities in Human T-Cell Lymphotropic Virus Type I-Associated Myelopathy

Author Affiliations

From the Third Department of Internal Medicine, Faculty of Medicine, Kagoshima (Japan) University.

Arch Neurol. 1989;46(5):513-516. doi:10.1001/archneur.1989.00520410047022

• Thirty-six patients with human T-cell lymphotropic virus type I (HTLV-I)—associated myelopathy were studied by electroencephalogram. Twenty-two of 36 patients showed mild to moderate electroencephalographic abnormalities, ranging from poor organization or slowing of the background activity to theta bursts and/ or spikes. None of these abnormalities were considered specific for HTLV-I—associated myelopathy. These electroencephalographic abnormalities had no apparent relationship to duration or severity of illness, nor to HTLV-I antibody titers in the cerebrospinal fluid. We document electroencephalographic changes in HTLV-I—associated myelopathy. Our data are consistent with previous reports describing the fact that involvement of regions above the spinal cord may exist in HTLV-I—associated myelopathy.

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