• Transient opsoclonus was observed in a patient who attempted suicide with the organophosphate insecticide Malathion (diethyl [dimethoxyphosphinothioyl] thiobutanedioate). Several toxins can cause opsoclonus, and these must be considered in its differential diagnosis. Eye movement disorders are one of the more common manifestations of organo-phosphate intoxication, and opsoclonus should now be included among these. Acetylcholine may be a neurotransmitter in the ocular motor pathway.
Pullicino P, Aquilina J. Opsoclonus in Organophosphate Poisoning. Arch Neurol. 1989;46(6):704–705. doi:10.1001/archneur.1989.00520420126037
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