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July 1989

Treatable Causes of Meningomyeloradiculitis in Individuals Infected With Human Immunodeficiency Virus-Reply

Author Affiliations

Department of Neurology St Louis University School of Medicine 3660 Vista Ave St Louis, MO 63110

Arch Neurol. 1989;46(7):723. doi:10.1001/archneur.1989.00520430017010

In Reply.—  As the Doctors Lanska state, the clinical-spinal fluid features of human immunodeficiency virus— related meningomyeloradiculopathy are so characteristic that it is probably the most recognizable, though uncommon, neurological syndrome seen in these patients. According to Miller et al,1 "AIDS-related subacute radiculomyelopathy is a unique syndrome." However, some non—human immunodeficiency virus—infected patients with leptomeningeal carcinomatosis have the syndrome.Early in my career, central nervous system tuberculosis and syphilis were fairly common diseases. I do not recall ever seeing a case of lumbosacral meningomyeloradiculopathy similar to those now being reported in individuals infected with human immunodeficiency virus. The experience of colleagues of my vintage is similar. Adams and Merritt2 reported only 15 cases of syphilitic meningomyelitis among 2231 patients with syphilis seen at the Boston (Mass) City Hospital and, as nearly as I can ascertain, none of these resembled the case reported by Lanska et al.3It might be

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