• We did not find a significant association between HLA antigens and pure autonomic failure or multiple system atrophy with autonomic failure. HLA-A32, specifically, did not occur with increased frequency in either group of patients. Our results do not support an HLA contribution in these disorders of the autonomic nervous system as reported by other investigators.
Nee LE, Brown RT, Polinsky RJ. HLA in Autonomic Failure. Arch Neurol. 1989;46(7):758–759. doi:10.1001/archneur.1989.00520430052016