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August 1989

Vascular Dementia and Dementia of Alzheimer-Type Cognition

Author Affiliations

Department of Neurology University of Genova Genova, Italy

Arch Neurol. 1989;46(8):839-840. doi:10.1001/archneur.1989.00520440019006

To the Editor.  —The article by Aharon-Peretz and coworkers1 in the July 1988 issue of the Archives, comparing the ventricular size and leuko-araiosis in multi-infarct and degenerative dementias, is of utmost interest to me.I wonder what kind of modification of the method used by Albert et al2 has been made. I cannot find any explanation of such low index values for multiinfarct dementia, with respect to ours.3 Considering the modifications of the method, an additional group of ageand sex-matched controls would have been more suitable for the purpose.However, the crucial point concerning this study refers, in my opinion, to 4 of 31 patients suffering from multiinfarct dementia, with a negative computed tomographic scan.O'Brien4 rightly pointed out that Hachinski's score divides patients into two subgroups: a large-infarct group and everything else. The modified ischemic score5 lends support to the diagnosis of large, and even