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November 1989

A New Sign of Neurofibromatosis on Magnetic Resonance Imaging of Children

Author Affiliations

From the Department of Radiology, Section of Neuroradiology, The Oregon Health Sciences University, Portland (Dr Goldstein), and the Departments of Neurology and Pediatrics (Dr Curless) and Radiology, Section of Neuroradiology (Dr Donovan Post), and Division of Magnetic Resonance Imaging (Dr Quencer), University of Miami (Fla) School of Medicine.

Arch Neurol. 1989;46(11):1222-1224. doi:10.1001/archneur.1989.00520470086032

• Ten pediatric patients with clinically proved neurofibromatosis underwent magnetic resonance imaging of the brain. Seven of these patients had lesions of increased signal intensity on T2-weighted images in the globus pallidus, brain stem, or cerebellar white matter. The lesions did not correlate with results of the neurologic examination or with developmental status. These abnormalities most likely represent hamartomas and should be recognized as part of the diagnostic spectrum of neurofibromatosis.