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July 1990

Isolated Pupil-Sparing Third-Nerve Palsy as the Presenting Sign of Multiple Sclerosis

Author Affiliations

From the Neuro-ophthalmology Unit, Massachusetts Eye and Ear Infirmary, and the Department of Ophthalmology, Harvard Medical School, Boston. Dr. Newman is now with the Neuro-ophthalmology Unit, Emory University, Atlanta, Ga.

Arch Neurol. 1990;47(7):817-818. doi:10.1001/archneur.1990.00530070117021

• A 27-year-old man presented with an isolated, pupil-sparing, partial third-nerve palsy. Etiologic investigations proved unrevealing. Subsequent development of an optic neuropathy prompted magnetic resonance imaging, which confirmed the clinical suspicion of multiple sclerosis. Rarely does multiple sclerosis present with oculomotor nerve involvement.

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