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April 1991

Internal Capsule Plaque and Tonic Spasms in Multiple Sclerosis

Author Affiliations

From the Department of Neurology and the Brain Research Institute, University of Chicago (Ill) (Drs Maimone and Reder), and the Department of Neurology, University of Catania (Italy) (Drs Finocchiaro and Recupero). Dr Maimone is now with the Istituto di Scienze Neurologiche, Universitá di Siena (Italy).

Arch Neurol. 1991;48(4):427-429. doi:10.1001/archneur.1991.00530160097021

• A patient developed hemilateral tonic spasms associated with a relapse of multiple sclerosis. An area of demyelination in the right internal capsule was observed on a magnetic resonance imaging scan. This lesion was not detectable on a second magnetic resonance imaging scan 10 months after the spasms had ceased. Paroxysmal symptoms in multiple sclerosis may represent transient phenomena related to inflammation in acute plaques.