• A patient developed hemilateral tonic spasms associated with a relapse of multiple sclerosis. An area of demyelination in the right internal capsule was observed on a magnetic resonance imaging scan. This lesion was not detectable on a second magnetic resonance imaging scan 10 months after the spasms had ceased. Paroxysmal symptoms in multiple sclerosis may represent transient phenomena related to inflammation in acute plaques.
Maimone D, Reder AT, Finocchiaro F, Recupero E. Internal Capsule Plaque and Tonic Spasms in Multiple Sclerosis. Arch Neurol. 1991;48(4):427–429. doi:10.1001/archneur.1991.00530160097021
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