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September 1991

Myoblast Transfer Therapy, vol 280, Advances in Experimental Medicine and Biology

Author Affiliations

Morgantown, WVa

Arch Neurol. 1991;48(9):899. doi:10.1001/archneur.1991.00530210025011

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Myoblast transfer represents an early exploitation in a therapeutic venture based on the tremendous advances made by molecular genetics. The possibility and promise of myoblast transfer therapy in the treatment of Duchenne muscular dystrophy and other inherited forms of muscle disease has raised the hopes and expectations of the public and, especially, affected individuals and their families.

This volume, a compilation of 35 presentations made at the International Conference on Myoblast Transfer Therapy in June 1989, is conveniently organized into seven general-topic sections relevant to myoblast therapy. The individual articles, which are well-written, short, and focused, present a realistic assessment of the challenges that will need to be addressed and mastered before myoblast transfer therapy can ever become "standard therapy." The discussions that follow individual articles and each general-topic section are very enlightening as they highlight many of the practical concerns and unresolved questions regarding myoblast transfer therapy.

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