—Our article1 was intended to describe an unusual group of patients with headache, increased intracranial pressure, and absence of papilledema. The differential diagnosis of increased intracranial pressure and related syndromes is extensive, and it was not our intention to review all such processes.With review of medical records, the symptoms of pharyngeal snoring, insomnia, restless or altered sleep pattern, nocturia, daytime somnolence, hallucinations, and hearing loss that are associated with obstructive sleep apnea were absent in our patients.2On the other hand, female predominance, pulsatile tinnitus, history of head trauma, empty sella syndrome, and chronic daily headache of great severity are seen commonly in our patients, but not necessarily in obstructive sleep apnea.Systemic hypertension is more common in obese individuals and may reflect the fact that both groups of patients are obese, rather than a true distinguishing characteristic of either syndrome. Although low protein concentration
Silberstein SD, Marcelis J. Idiopathic Intracranial Hypertension Without Papilledema: Related to Sleep Apnea?-Reply. Arch Neurol. 1992;49(1):14. doi:10.1001/archneur.1992.00530250018005
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