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February 1992

Neurobiology of Incontinence

Author Affiliations

Rochester, NY

Arch Neurol. 1992;49(2):127. doi:10.1001/archneur.1992.00530260025006

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Incontinence, a common problem with a diverse underlying pathogenesis, is treatable by a variety of specialists. Neurobiology of Incontinence is the result of a multidisciplinary symposium sponsored by the Ciba Foundation that emphasized the neurologic aspects of both urinary and fecal incontinence. Each chapter of this book consists of a review of the topic by a well-known investigator, followed by a discussion by the symposium's participants. The first section of the book includes well-written chapters covering the relevant anatomy, neurophysiology, and pharmacology, with the bulk of the material focused on urinary incontinence. The present state of knowledge regarding the complex interaction of cortical function and autonomic reflex pathways required for normal bowel and bladder function is succinctly presented. The book includes information on the actions of a number of neurotransmitters on voiding function; the importance of this information is, at present, still speculative.

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