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May 1992

Albendazole Therapy for Giant Subarachnoid Cysticerci

Author Affiliations

From the Neurologic Service, Regional Hospital of the Ecuadorian Institute of Social Security of Guayaquil (Ecuador) (Drs Del Brutto, Aguirre, Díaz-Calderón, and Alarcón), and the Research Division, National Institute of Neurology and Neurosurgery of Mexico, Mexico City (Dr Sotelo).

Arch Neurol. 1992;49(5):535-538. doi:10.1001/archneur.1992.00530290123021

• Albendazole is considered to be the drug of choice for treatment of parenchymal brain cysticercosis. Its efficacy, however, for treatment of subarachnoid cysticerci has not been established, to our knowledge. In this study, we treated four patients who had giant subarachnoid cysticerci with albendazole at daily doses of 15 mg/kg of body weight for 8 days. Computed tomographic studies showed that all cysts disappeared 3 months after the end of treatment. This was associated with marked clinical improvement in every case. Our results indicated that albendazole is highly effective for treatment of this form of the disease.

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